Protective Coatings
Many active ingredients require a protective coating to increase their stability and improve their mechanical properties. Protective EUDRAGIT® coatings dissolve in the acid medium of the stomach to rapidly release the active ingredient. They seal sensitive actives and increase patient compliance by masking tastes and odors. Even thin layers of EUDRAGIT® provide the desired effect, making it an extremely economical application. Pharma Polymers offer various cationic EUDRAGIT® E grades for protective coatings.
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Applications
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EUDRAGIT® Grades
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Availability
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Functionality
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Dissoltion Properties |
Monographs + DMFs
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Taste masking, odor masking |
EUDRAGIT® E 100 |
Granules |
Cationic polymer with dimethylaminoethyl methacrylate as a functional group |
Soluble in gastric fluid up to pH 5.0
Swellable and permeable above pH 5.0 |
Ph.Eur., JPE, DMF 1242 |
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Insulating coatings |
EUDRAGIT® E PO |
Powder |
Ph.Eur., JPE, DMF 1242 |
Application benefits of protective EUDRAGIT® coatings:
- PH-dependent drug release
- Protection of sensitive actives
- Taste and odor masking
- Moisture protection
- Good storage stability
- Improved passage of the dosage form
- Smooth and glossy surfaces, good colorcoating